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Use lanthanide doped nanoparticle to see, to touch, to feel the nanoscale world

Date: 2022-09-30
Time: 10:00
Venue: M253
Speaker: 王帆 教授



Upconversion nanoparticles (UCNP) is a lanthanide ion-doped nanocrystal that has a natural nonlinear photo-response from their upconverting energy transfer process. The nonlinearity can be further modified by changing the doping element and concentration. Here we present a strategy that applies UCNPs as near-infrared (NIR) nonlinear fluorescence probe for in-depth super-resolution imaging, including NIR saturation microscopy, Bessel-NIR saturation microscopy and NIR nonlinear structured illumination microscopies. Most recently, upon these advances, we have found that the thousands of Lanthanide ions provide a strong dielectric resonance effect in a single UCNP. We will report the ion resonance effect in UCNPs could substantially increase the permittivity and polarizability of nanocrystals, leading to an enhanced optical force on a single 23.3 nm radius UCNP, more than 30 times stronger than the reported value for gold nanoparticles with the same size. We further report that the resonance effect could engineer the Rayleigh scattering of UCNPs. When the resonance condition is fulfilled, the scattering will be enhanced. We use interferometric scattering microscopy (iSCAT) to verify the resonance scattering feature and demonstrate a new mode of multiplexed iSCAT.


Prof. Fan Wang leads the biophotonics research group at the School of Physics, Beihang University. Prof. Wang has expertise in optoelectronics, biophotonics, and nanomaterials. He also has expertise in biophotonics application of nanomaterials, including super-resolution microscopy, optical tweezers, single nanoparticle tracking and sensing. Prof. Wang has published over 73 peer-reviewed journal articles (including 13 Nature series journals), including leading author articles in Nature Nanotechnology,Nature Communications x2,Light: Science & Applications,Optica,Nano Letters x6,small, Advanced Science和Advanced Materials, with an h-index of 35 and over 4783 citations. Prof. Wang obtained his Ph.D. from the University of New South Wales in 2014. In 2019, he was awarded the UTS Chancellor’s Postdoctoral Research Fellowship to establish his biophotonics research team. In 2020, he obtained the Australia Discovery Early Career Researcher Award to conduct his biological laser cooling technology research, and he joined the School of Electrical and Data Engineering to establish his group. In 2021, he was awarded the David Syme research prize and iCANX Young Scientist Awards due to his biophotonics research. In 2022, he joined Beihang University to establish his group in China..